The Distribution of Mitochondrial DNA Heteroplasmy Due to Random Genetic Drift
نویسندگان
چکیده
منابع مشابه
Evolution of recombination due to random drift.
In finite populations subject to selection, genetic drift generates negative linkage disequilibrium, on average, even if selection acts independently (i.e., multiplicatively) upon all loci. Negative disequilibrium reduces the variance in fitness and hence, by Fisher's (1930) fundamental theorem, slows the rate of increase in mean fitness. Modifiers that increase recombination eliminate the nega...
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Random Genetic Drift is one of the evolutionary forces that effects the distribution of alleles and changes their frequencies in populations. The main idea behind this theory is that genetic changes can happen randomly. This can be explained through the Bottleneck effect. There are two main factors that have an influence on genetic drift, the first one is the Effective Population Size Ne , whic...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2008
ISSN: 0002-9297
DOI: 10.1016/j.ajhg.2008.10.007